TACE plus radiotherapy improves outcomes in poor-prognosis hepatocellular carcinoma
FROM JAMA ONCOLOGY
Use of transarterial chemoembolization (TACE) plus external beam radiotherapy may improve outcomes in patients with hepatocellular carcinoma (HCC) showing macroscopic vascular invasion, according to results of a recent randomized study.
The TACE plus radiotherapy approach was well tolerated and improved progression-free survival compared with sorafenib treatment, investigators wrote. The report was published in JAMA Oncology.
“The results of this study represent a significant advance in addressing an urgent unmet need in treating patients with advanced HCC,” noted Sang Min Yoon, MD, PhD, of the department of radiation oncology, University of Ulsan College of Medicine, Seoul, Republic of Korea, and coauthors.
Patients with HCC that shows macroscopic vascular invasion are a particularly poor prognosis subset, according to Dr. Yoon and coauthors.
