Antacid use in infants linked to increased fracture risk

SAN FRANCISCO – Children were more likely to experience a fracture if they were prescribed antacids before age 1 year, according to a study of military families.

The large study revealed that use of proton pump inhibitors (PPIs) before age 1 year was linked to a 22% increased risk of fracture, compared with those not prescribed antacids. Similarly, children prescribed both PPIs and H₂ blockers before age 1 year were 31% more likely to have a fracture compared to those not taking the drugs.