Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Black-White Disparities in Breast Cancer Survival

J Clin Oncol; ePub 2017 Oct 16; Jemal, et al

Excess relative risk of all-cause death in nonelderly black women diagnosed with stage I to III breast cancer was greater than in white women, with insurance accounting for one-third of the excess risk, followed by tumor characteristics. This according to a study that examined the factors contributing to black-white disparities in survival among nonelderly women with breast cancer between 2004 and 2013. Researchers found:

  • 563,497 white and black women aged 18 to 64 years and diagnosed with stage I to III breast cancer from 2004 to 2013 were included.
  • Among women with hormone receptor-positive disease (78% of all patients), the HR for death in black vs white women was 2.05.
  • This HR decreased to 1.93, 1.54, 1.30, and 1.25 when sequentially matched for comorbidity, insurance, tumor characteristics, and treatment, respectively.
  • These factors combined accounted for 76.3% of the total excess risk of death in black patients: insurance (37.0%), tumor characteristics (23.2%), comorbidities (11.3%), and treatment (4.8%).

Citation:

Jemal A, Robbins AS, Lin CC, et al. Factors that contributed to black-white disparities in survival among nonelderly women with breast cancer between 2004 and 2013. [Published online ahead of print October 16, 2017]. J Clin Oncol. doi:10.1200/JCO.2017.73.7932.

This Week's Must Reads

ACOG Offers Guidance on Management of GDM, Obstet Gynecol; ePub 2018 Feb; ACOG, Turrentine

Effect of Hormone Therapy on Incident Hypertension , Menopause; ePub 2018 Jan 29; Swica, et al

Interest in OTC Access to Progestin-Only Pills, Women’s Health Issues; ePub 2018 Jan 29; Grindlay, et al

Missed Breast Cancers in High Risk MRI Screening, Breast Cancer Res Treat; ePub 2018 Jan 31; Vreemann, et al

ACOG Recommendations: Fatigue and Patient Safety, Obstet Gynecol; ePub 2018 Feb; ACOG, Gregg

Must Reads in Breast Cancer

Missed Breast Cancers in High Risk MRI Screening, Breast Cancer Res Treat; ePub 2018 Jan 31; Vreemann, et al

Black-White Disparities in Breast Cancer Survival, J Clin Oncol; ePub 2017 Oct 16; Jemal, et al

Mammography Screening Patterns Evaluated, Womens Health Issues; ePub 2017 Sep 18; Jacobson, et al

FDA Approves New Mammography Device, FDA news release; 2017 Sep 1