Midtrimester cervical shortening linked with aberrant uterine electromyographic signals

Key clinical point: The frequency of short-burst and burst uterine electromyography signals is higher in midtrimester pregnant women with a cervical length (CL) <2.5 cm, thus elucidating the biophysiological basis for midtrimester cervical shortening that may be used to predict preterm birth.

Major finding: Women with a short vs. normal CL showed significantly higher median percentages of short-bursts (17.3% vs. 2.5%; P = .001) and bursts (6.6% vs. 0%; P = .014).

Study details: Findings are from a prospective cohort study including 28 women with a singleton non-anomalous pregnancy between 16 weeks 0 days and 22 weeks 6 days of gestation, of which 10 and 18 women had a CL of ≥3 cm (normal) and <2.5 cm (short), respectively.

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Disclosures: The study was funded by PreTeL, Inc. RC Young declared being the founder of PreTeL.

Source: Marinescu PS et al. Mid-trimester uterine electromyography in patients with a short cervix. Am J Obstet Gynecol. 2022 (Mar 26). Doi: 10.1016/j.ajog.2022.03.046