Drug-induced immune hemolytic anemia associated with albumin-bound paclitaxel
The Journal of Community and Supportive Oncology. 2015 August;13(8):298-299 | 10.12788/ jcso.0160
August 25, 2015|The Journal of Community and Supportive Oncology
Drug-induced immune hemolytic anemia is rare, with only 1 patient in 1 million affected by the condition. Garratty identified 125 drugs indicated in DIIHA of which 11% were antineoplastic agents, and neither paclitaxel nor albumin-bound paclitaxel were included. In addition, we did not find any reports in our own search of the literature. Taxanes are known to cause anemia as a result of their myelosuppressive effects, but an immune hemolysis is rare. To our knowledge, we present here the first case of DIIHA with nab-paclitaxel.
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