Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Viral Hepatitis Diagnosis & Linkage to Care

J Viral Hepat; ePub 2017 Aug 2; de la Torre, et al

Use of audio-computer-assisted survey interview (audio-CASI) can identify patients at risk for hepatitis C virus (HCV) or hepatitis B virus (HBV) infection and those in need of HBV vaccination in urban medical centers, a recent study found. In the study, audio-CASI was used to guide HCV and HBV infection testing in urban clinics and risk reporting, blood testing and serology results were compared to historical controls. A patient navigator (PN) followed up blood test results and provided patients with positive serology linkage to care (LTC). Researchers found:

  • Of 1,932 patients surveyed, 574 (30%) were at risk for chronic viral hepatitis.
  • 254 (44.3%) patients were tested, 34 (13.5%) had serology warranting treatment evaluation, and 64% required HBV vaccination.
  • Of 16 patients with infection, 7 HCV and 3 HBV patients started treatment following LTC.
  • The average monthly HCV antibody testing increased from 245 (January-June) to 1,187 (July-October).


de la Torre AN, Castaneda I, Ahmad M, et al. Audio-computer-assisted survey interview and patient navigation to increase chronic viral hepatitis diagnosis and linkage to care in urban health clinics. [Published online ahead of print August 2, 2017]. J Viral Hepat. doi:10.1111/jvh.12744.

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HCV Treatment as Prevention in PWIDs, Lancet; 2018 Feb; Zelenev, Li, et al

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Opioid Substitution Therapy in HCV Patients, J Infect Dis; ePub 2017 Dec 26; Stepanova, et al

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