Gastric cancer: Diagnostic accuracy of esophagogastroduodenoscopy depends on gastric observation time

Key clinical point: A shorter gastric observation time during index esophagogastroduodenoscopy (EGD; preceding gastric cancer diagnosis) serves as an important predictor of the occurrence of interval advanced gastric cancer.

Major finding: A shorter observation time (<3 min; adjusted odds ratio 2.27;  95% CI 1.20-4.30) at preceding endoscopy was independently associated with an increased risk for interval advanced gastric cancer.

Study details: Findings are from a retrospective nested case-control study that included 1257 patients diagnosed with gastric cancer within 6-36 months of “cancer-negative” index EGD, of which 102 patients had advanced gastric cancer.

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Disclosures: This study was supported by the Research Fund of the Korean Society of Gastroenterology and a National Research Foundation of Korea grant funded by the Korea government. The authors declared no conflicts of interest.

Source: Kim TJ et al. Interval advanced gastric cancer after negative endoscopy. Clin Gastroenterol Hepatol. 2022 (Sep 5). Doi: 10.1016/j.cgh.2022.08.027