Negative FDG‐avid lesions in proximal colon ensure absence of additional lesions other than target CRC

Key clinical point: Among patients with stenotic left‐sided colorectal cancer (CRC) who underwent incomplete colonoscopy, absence of negative preoperative 18‐fluoro‐2‐deoxy‐glucose (FDG)‐avid lesions in the proximal colon other than the target CRC ensures the absence of additional lesions warranting changes in surgical plan.

Major finding: The cumulative detection rate of advanced adenoma was significantly higher in the incomplete vs complete colonoscopy group at 1 year (6.3% vs 0.7%) and 5 years (12.5% vs 9.9%; P = .012). However, the cumulative rate of detection of adenocarcinoma at 1 and 5 years (P = .15) and 5-year cumulative rate of additional surgery (P = .85) were not different between the groups.

Study details: Findings are from an analysis of 754 patients with left‐sided CRC without synchronous FDG‐avid lesions on preoperative 18‐FDG positron emission tomography/computed tomography. Patients were categorized into those who underwent complete (n=616) and incomplete (n=138) preoperative colonoscopy.

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Disclosures: This study was funded by the Korea Institute of Radiological and Medical Sciences, funded by the Ministry of Science and ICT, Republic of Korea. The authors declare no competing interests.

Source: Lee JI et al. Sci Rep. 2021 Jul 19. doi: 10.1038/s41598-021-94030-w.