Combination Treatment With Memantine Has Long-Term Benefits

Combining memantine with the cholinesterase inhibitor (ChEI) donepezil is better than the ChEI alone for patients with moderate-to-severe Alzheimer disease (AD) in all key domains, including cognition, function, behavior, global outcome, and care dependency, according to researchers from McGill Centre for Studies in Aging in Montreal, Canada, and the Clinical Institute of Neurosciences, Hospital Clínic, in Barcelona, Spain.