Opioid Delivery and Granuloma Formation, and Is Lipid Monitoring Getting Short Shrift?

Administering opioids into the intrathecal space means the drug is highly localized, so lower doses are possible. Nonetheless, one of the possible adverse effects is an intrathecal granuloma due to an inflammatory reaction at the level of the catheter tip. The complication is rare but very risky if not detected and treated properly.