Locking Out Bacteria

How effective is an antibiotic lock— instillation of a concentrated antibiotic-anticoagulant solution into the catheter lumens during the interdialytic period—at treating Enterococcus catheter-related bacteremia (CRB)? Expanding on prior research completed at their facility, investigators from the University of Alabama, Birmingham evaluated the outcomes of 64 patients who were undergoing hemodialysis and had vancomycin-sensitive Enterococcus CRB.