Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Fractional CO2 Laser Efficient Scar Treatment

Lasers Med Sci; 2017 Dec; Elcin, Yalici-Armagan

Fractional carbon dioxide laser is an efficient treatment option for acne scars and furthermore, self-assessment results show that more than half of the participants still experience at least mild improvement at the end of 3 years. This according to a recent study that evaluated the efficacy and safety of fractional carbon dioxide laser treatment of acne scars. 31 participants, 15 female and 16 male, whose mean age was 34.84 ± 10.94 years, were included in the study, which took place between 2012 and 2016. Participants received 2 or 3 treatment sessions at 4-week intervals, with a 10,600 nm fractional carbon dioxide laser with pulse energies ranging between 100 and 160 mJ, 120 spot type, 75–100 spot/cm2 density, and 30 W power. Researchers found:

  • The grade of improvement at the short-term evaluation was as follows: No improvement, mild, moderate, and significant improvement for 7 (22.6%), 11 (35.5%), 9 (29%), and 4 (12.9%) of the participants, respectively.
  • Regarding self-assessments, 80.6 and 61.3% of the participants rated themselves as having at least mild improvement at the short-term and the long-term follow-up periods, respectively.


Elcin G, Yalici-Armagan B. Fractional carbon dioxide laser for the treatment of facial atrophic acne scars: Prospective clinical trial with short and long-term evaluation. 2017;32(9):2047-2054. doi:10.1007/s10103-017-2322-7.

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