Familial Confluent and Reticulate Papillomatosis Successfully Treated With Minocycline

Confluent and reticulate papillomatosis (CRP) is an idiopathic disorder characterized by persistent patches and plaques that are centrally confluent and peripherally reticulate. Although CRP primarily occurs sporadically, there may be a familial predisposition to the development of CRP. Minocycline has been reported as effective in the treatment of CRP, seemingly due to its antimicrobial and anti-inflammatory activity. We describe a case of familial CRP involving 2 brothers who were successfully treated with minocycline.