Long-term Follow-up in a Case of Pemphigus

Pemphigus is a chronic, autoimmune, epidermal immunobullous disorder with potentially fatal outcomes. It is caused by autoantibodies directed against components of the intercellular adhesion complex, desmoglein 1, and desmoglein 3. In India, pemphigus occurs in a younger age group compared to other populations, and childhood pemphigus also is common. The natural course of the disease is characterized by remissions and relapses. Most relapses occur within 2 years after the diagnosis, but late recurrences are well documented.