Florid Reactive Periostitis of the Hand

Florid reactive periostitis is a relatively rare lesion that most often develops in the tubular bones of the hands and feet. This lesion can easily be confused with malignant or infectious processes. Correlation of physical examination and radiographic findings with histologic findings usually is diagnostic. Excisional biopsy with careful removal of all diseased tissue is most often curative. However, recurrent cases have been described as sometimes requiring ablative procedures.