Estrogen Plus Progestin Therapy—Increased Risk for CAD?

For the first few years after starting estrogen plus progestin therapy, postmenopausal women are at greater risk of developing coronary artery disease (CAD). Researchers from the Harvard School of Public Health, Boston, MA; the Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA; and the National Heart, Lung, and Blood Institute, Bethesda, MD sought to determine whether this increased risk disappears over time.