Rodney A. Appell, MD F. Brantley Scott Professor of Voiding Dysfunction, Department of Urology, Baylor College of Medicine, Houston
Address: Rodney A. Appell, MD, Department of Urology, Baylor College of Medicine, 6560 Fannin, Suite 2100, Houston, TX 77030; e-mail rappell@bcm.tmc.edu
Dr. Appell has received grant and research support from Alza Corporation, is a consultant for the Alza and Pharmacia corporations, and is on the speakers’ bureau of Pharmacia.
ABSTRACTTwo newer antimuscarinic anticholinergic drugs—tolterodine and extended-release oxybutynin—are approximately as effective in treating overactive bladder as immediate-release oxybutynin, but are more tolerable. I review clinical trial data on the newer agents.