Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Risk of Pregnancy Loss & Ambient Air Pollution

Fertil Steril; ePub 2017 Nov 16; Ha, et al

Exposure to air pollution throughout pregnancy is associated with pregnancy loss, a recent study found. The cohort study included 343 singleton pregnancies with detailed protocols for ovulation and pregnancy testing. Researchers found:

  • The incidence of pregnancy loss was 28%.
  • An interquartile range increase in average whole pregnancy ozone (HR, 1.12) and particulate matter <2.5 µm (HR, 1.13) concentrations were associated with faster time to pregnancy loss.
  • Sulfate compounds also increased risk (HR, 1.58).
  • Last 2 weeks of exposures were not associated with loss.

Citation:

Ha S, Sundaram R, Buck Louis GM, et al. Ambient air pollution and the risk of pregnancy loss: A prospective cohort study. [Published online ahead of print November 16, 2017]. Fertil Steril. doi:10.1016/j.fertnstert.2017.09.037.

This Week's Must Reads

Obesity & Contraceptive Use Among Younger Women, Contraception; ePub 2017 Dec 5; Mosher, et al

Do Vasomotor Symptoms Elevate Diabetes Risk?, Menopause; ePub 2017 Dec 4; Gray, Katon, et al

Risk of Seizure Disorder After Eclampsia Evaluated, Obstet Gynecol; 2017 Dec; Nerenberg, Park, et al

Endometriosis & Risk of Adverse Pregnancy Outcomes, Fertil Steril; ePub 2017 Nov 29; Chen, et al

Must Reads in Obstetrics

Risk of Seizure Disorder After Eclampsia Evaluated, Obstet Gynecol; 2017 Dec; Nerenberg, Park, et al

Endometriosis & Risk of Adverse Pregnancy Outcomes, Fertil Steril; ePub 2017 Nov 29; Chen, et al

Chronic Conditions in Women Hospitalized for Delivery, Obstet Gynecol; ePub 2017 Nov 3; Admon, et al

Does Aspirin Prevent Preterm Preeclampsia?, Am J Obstet Gynecol; ePub 2017 Nov 11; Roberge, et al

Pulse Pressure & Risk of Postepidural Complications, Obstet Gynecol; ePub 2017 Nov 3; Lappen, et al