Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Increasing Incidence of MS in Puerto Rico

Neuroepidemiology; 2017 Nov; Chinea, et al

Multiple sclerosis (MS) incidence estimates for Puerto Rico (PR) were higher than other countries in Latin America and the Caribbean (LAC) but consistent with MS increases in other world regions, a recent study found. This study examined trends of MS incidence over 4 years and to provide age- and gender-standardized incidence rate estimates for a Caribbean island. Data from the PR MS Foundation’s registry was used to identify all newly diagnosed MS cases between 2013 and 2016. MS patients were aged ≥18 years and met the 2010 revised McDonald criteria. Researchers found:

  • A total of 583 new MS cases were diagnosed in PR from 2013 to 2016.
  • The age- and gender-standardized MS incidence rate for PR increased from 6.1/100,000 in 2013 to 6.7/100,000 in 2016.
  • The annual age-standardized MS incidence rates for females rose from 8.4/100,000 in 2013 to 9.8/100,000 in 2016 and were higher than males, which remained around 3.7/100,000.


Chinea A, Ríos-Bedoya CF, Vicente I, et al. Increasing incidence and prevalence of multiple sclerosis in Puerto Rico (2013–2016). Neuroepidemiology. 2017;49:106-112. doi:10.1159/000484090.

This Week's Must Reads

Possible Link: Hepatic Steatosis and Brain Aging, JAMA Neurol; ePub 2017 Nov 20; Weinstein, et al

Neurologic Drug Shortages May Compromise Care, Neurology; ePub 2017 Nov 15; Omorodion, et al

Sleep Fragmentation Linked with PD in Older Adults, Mov Disord; ePub 2017 Oct 30; Sohail, Yu, et al

Dietary Sodium to Potassium Ratio and Stroke Risk, Stroke; ePub 2017 Oct 10; Willey, Gardener, et al

Sleep Apnea Did Not Accelerate Kidney Decline, Sleep; ePub 2017 Nov 3; Canales, Hagen, et al

Must Reads in Multiple Sclerosis

Consistent Definition of Physical Activity Lacking, Disabil Rehabil; ePub 2017 Nov 7; Kinnett-Hopkins, et al

Dual-Task Performance Assessed in Persons with MS, Arch Phys Med Rehabil; ePub 2017 Nov 3; Goverover, et al

Increasing Incidence of MS in Puerto Rico, Neuroepidemiology; 2017 Nov; Chinea, et al

Sleep Problems and Cognitive Dysfunction in MS, Behav Sleep Med; 2018 Jan-Feb; Hughes, et al

Body Composition Examined in Persons with MS, Disabil Health J; ePub 2017 Oct 16; Wingo, et al